MEDICATION SAFETY ISSUES
Sound-alike/look-alike issues:
Betadine® may be confused with Betagan®, betaine
U.S. BRAND NAMES — AK-Poly-Bac™ ; Polysporin® [OTC]
PHARMACOLOGIC CATEGORY
Antibiotic, Ophthalmic
Antibiotic, Topical
DOSING: ADULTS
Ophthalmic infection: Ophthalmic (ointment): Instill 1/2" ribbon in the affected eye(s) every 3-4 hours for acute infections or 2-3 times/day for mild-to-moderate infections for 7-10 days.
Superficial dermal infection: Topical ointment/powder: Apply to affected area 1-4 times/day; may cover with sterile bandage if needed.
DOSING: PEDIATRIC — Refer to adult dosing.
(For additional information see "Bacitracin and polymyxin B: Pediatric drug information")
DOSING: ELDERLY — Refer to adult dosing.
DOSAGE FORMS — Excipient information presented when available (limited, particularly for generics); consult specific product labeling.
Ointment, ophthalmic: Bacitracin 500 units and polymyxin B 10,000 units per g (3.5 g)
AK-Poly-Bac™ : Bacitracin 500 units and polymyxin 10,000 units per g (3.5 g)
Ointment, topical: Bacitracin 500 units and polymyxin B 10,000 units per g in white petrolatum (15 g, 30 g)
Polysporin®: Bacitracin 500 units and polymyxin B 10,000 units per g (0.9 g, 15 g, 30 g)
Powder, topical:
Polysporin®: Bacitracin 500 units and polymyxin B 10,000 units per g (10 g)
DOSAGE FORMS: CONCISE
Ointment, ophthalmic: Bacitracin 500 units and polymyxin B 10,000 units per g (3.5 g)
AK-Poly-Bac™ : Bacitracin 500 units and polymyxin 10,000 units per g (3.5 g)
Ointment, topical: Bacitracin 500 units and polymyxin B 10,000 units per g in white petrolatum (15 g, 30 g)
Polysporin®: Bacitracin 500 units and polymyxin B 10,000 units per g (0.9 g, 15 g, 30 g)
Powder, topical:
Polysporin®: Bacitracin 500 units and polymyxin B 10,000 units per g (10 g)
GENERIC EQUIVALENT AVAILABLE — Yes
USE — Treatment of superficial infections caused by susceptible organisms
ADVERSE REACTIONS SIGNIFICANT — 1% to 10%: Local: Rash, itching, burning, anaphylactoid reactions, swelling, conjunctival erythema
CONTRAINDICATIONS — Hypersensitivity to bacitracin, polymyxin B, or any component of the formulation
DRUG INTERACTIONS
Capreomycin: May enhance the neuromuscular-blocking effect of Polymyxin B. Risk C: Monitor therapy
Colistimethate: Polymyxin B may enhance the neuromuscular-blocking effect of Colistimethate. Risk C: Monitor therapy
Neuromuscular-Blocking Agents: Polymyxin B may enhance the neuromuscular-blocking effect of Neuromuscular-Blocking Agents. Risk D: Consider therapy modification
PREGNANCY RISK FACTOR — C (show table)
PREGNANCY IMPLICATIONS — Animal reproduction studies have not been conducted with this combination; therefore, Bacitracin and Polymyxin B is considered pregnancy category C. See individual agents.
LACTATION — Excretion in breast milk unknown/use caution
BREAST-FEEDING CONSIDERATIONS — It is not known if bacitracin or polymyxin B is found in breast milk. The manufacturer recommends that caution be exercised when administering Bacitracin and Polymyxin B to nursing women. See individual agents.
PRICING — (data from drugstore.com)
Ointment (Bacitracin-Polymyxin B)
500-10000 units/g (3.5): $17.99
CANADIAN BRAND NAMES — LID-Pack®; Optimyxin®
INTERNATIONAL BRAND NAMES — Glubacida (MX); Miratracina (CO); Nebacetina (MX); Neobacitracine (BE); Neospor & iacute;n Dermico (MX); Polisulfade (PT); Polixin Ungena (MX); Polyfax (MY); Polysporin Ophthalmic (ZA); Tribiot (MX)
MECHANISM OF ACTION — See individual agents.
PHARMACODYNAMICS / KINETICS — See individual agents.
Showing posts with label Bacitracin and polymyxin B. Show all posts
Showing posts with label Bacitracin and polymyxin B. Show all posts
Sunday, May 30, 2010
Bacitracin and polymyxin B
MEDICATION SAFETY ISSUES
Sound-alike/look-alike issues:
Betadine® may be confused with Betagan®, betaine
U.S. BRAND NAMES — AK-Poly-Bac™ ; Polysporin® [OTC]
PHARMACOLOGIC CATEGORY
Antibiotic, Ophthalmic
Antibiotic, Topical
DOSING: ADULTS
Ophthalmic infection: Ophthalmic (ointment): Instill 1/2" ribbon in the affected eye(s) every 3-4 hours for acute infections or 2-3 times/day for mild-to-moderate infections for 7-10 days.
Superficial dermal infection: Topical ointment/powder: Apply to affected area 1-4 times/day; may cover with sterile bandage if needed.
DOSING: PEDIATRIC — Refer to adult dosing.
(For additional information see "Bacitracin and polymyxin B: Pediatric drug information")
DOSING: ELDERLY — Refer to adult dosing.
DOSAGE FORMS — Excipient information presented when available (limited, particularly for generics); consult specific product labeling.
Ointment, ophthalmic: Bacitracin 500 units and polymyxin B 10,000 units per g (3.5 g)
AK-Poly-Bac™ : Bacitracin 500 units and polymyxin 10,000 units per g (3.5 g)
Ointment, topical: Bacitracin 500 units and polymyxin B 10,000 units per g in white petrolatum (15 g, 30 g)
Polysporin®: Bacitracin 500 units and polymyxin B 10,000 units per g (0.9 g, 15 g, 30 g)
Powder, topical:
Polysporin®: Bacitracin 500 units and polymyxin B 10,000 units per g (10 g)
DOSAGE FORMS: CONCISE
Ointment, ophthalmic: Bacitracin 500 units and polymyxin B 10,000 units per g (3.5 g)
AK-Poly-Bac™ : Bacitracin 500 units and polymyxin 10,000 units per g (3.5 g)
Ointment, topical: Bacitracin 500 units and polymyxin B 10,000 units per g in white petrolatum (15 g, 30 g)
Polysporin®: Bacitracin 500 units and polymyxin B 10,000 units per g (0.9 g, 15 g, 30 g)
Powder, topical:
Polysporin®: Bacitracin 500 units and polymyxin B 10,000 units per g (10 g)
GENERIC EQUIVALENT AVAILABLE — Yes
USE — Treatment of superficial infections caused by susceptible organisms
ADVERSE REACTIONS SIGNIFICANT — 1% to 10%: Local: Rash, itching, burning, anaphylactoid reactions, swelling, conjunctival erythema
CONTRAINDICATIONS — Hypersensitivity to bacitracin, polymyxin B, or any component of the formulation
DRUG INTERACTIONS
Capreomycin: May enhance the neuromuscular-blocking effect of Polymyxin B. Risk C: Monitor therapy
Colistimethate: Polymyxin B may enhance the neuromuscular-blocking effect of Colistimethate. Risk C: Monitor therapy
Neuromuscular-Blocking Agents: Polymyxin B may enhance the neuromuscular-blocking effect of Neuromuscular-Blocking Agents. Risk D: Consider therapy modification
PREGNANCY RISK FACTOR — C (show table)
PREGNANCY IMPLICATIONS — Animal reproduction studies have not been conducted with this combination; therefore, Bacitracin and Polymyxin B is considered pregnancy category C. See individual agents.
LACTATION — Excretion in breast milk unknown/use caution
BREAST-FEEDING CONSIDERATIONS — It is not known if bacitracin or polymyxin B is found in breast milk. The manufacturer recommends that caution be exercised when administering Bacitracin and Polymyxin B to nursing women. See individual agents.
PRICING — (data from drugstore.com)
Ointment (Bacitracin-Polymyxin B)
500-10000 units/g (3.5): $17.99
CANADIAN BRAND NAMES — LID-Pack®; Optimyxin®
INTERNATIONAL BRAND NAMES — Glubacida (MX); Miratracina (CO); Nebacetina (MX); Neobacitracine (BE); Neospor & iacute;n Dermico (MX); Polisulfade (PT); Polixin Ungena (MX); Polyfax (MY); Polysporin Ophthalmic (ZA); Tribiot (MX)
MECHANISM OF ACTION — See individual agents.
PHARMACODYNAMICS / KINETICS — See individual agents.
Sound-alike/look-alike issues:
Betadine® may be confused with Betagan®, betaine
U.S. BRAND NAMES — AK-Poly-Bac™ ; Polysporin® [OTC]
PHARMACOLOGIC CATEGORY
Antibiotic, Ophthalmic
Antibiotic, Topical
DOSING: ADULTS
Ophthalmic infection: Ophthalmic (ointment): Instill 1/2" ribbon in the affected eye(s) every 3-4 hours for acute infections or 2-3 times/day for mild-to-moderate infections for 7-10 days.
Superficial dermal infection: Topical ointment/powder: Apply to affected area 1-4 times/day; may cover with sterile bandage if needed.
DOSING: PEDIATRIC — Refer to adult dosing.
(For additional information see "Bacitracin and polymyxin B: Pediatric drug information")
DOSING: ELDERLY — Refer to adult dosing.
DOSAGE FORMS — Excipient information presented when available (limited, particularly for generics); consult specific product labeling.
Ointment, ophthalmic: Bacitracin 500 units and polymyxin B 10,000 units per g (3.5 g)
AK-Poly-Bac™ : Bacitracin 500 units and polymyxin 10,000 units per g (3.5 g)
Ointment, topical: Bacitracin 500 units and polymyxin B 10,000 units per g in white petrolatum (15 g, 30 g)
Polysporin®: Bacitracin 500 units and polymyxin B 10,000 units per g (0.9 g, 15 g, 30 g)
Powder, topical:
Polysporin®: Bacitracin 500 units and polymyxin B 10,000 units per g (10 g)
DOSAGE FORMS: CONCISE
Ointment, ophthalmic: Bacitracin 500 units and polymyxin B 10,000 units per g (3.5 g)
AK-Poly-Bac™ : Bacitracin 500 units and polymyxin 10,000 units per g (3.5 g)
Ointment, topical: Bacitracin 500 units and polymyxin B 10,000 units per g in white petrolatum (15 g, 30 g)
Polysporin®: Bacitracin 500 units and polymyxin B 10,000 units per g (0.9 g, 15 g, 30 g)
Powder, topical:
Polysporin®: Bacitracin 500 units and polymyxin B 10,000 units per g (10 g)
GENERIC EQUIVALENT AVAILABLE — Yes
USE — Treatment of superficial infections caused by susceptible organisms
ADVERSE REACTIONS SIGNIFICANT — 1% to 10%: Local: Rash, itching, burning, anaphylactoid reactions, swelling, conjunctival erythema
CONTRAINDICATIONS — Hypersensitivity to bacitracin, polymyxin B, or any component of the formulation
DRUG INTERACTIONS
Capreomycin: May enhance the neuromuscular-blocking effect of Polymyxin B. Risk C: Monitor therapy
Colistimethate: Polymyxin B may enhance the neuromuscular-blocking effect of Colistimethate. Risk C: Monitor therapy
Neuromuscular-Blocking Agents: Polymyxin B may enhance the neuromuscular-blocking effect of Neuromuscular-Blocking Agents. Risk D: Consider therapy modification
PREGNANCY RISK FACTOR — C (show table)
PREGNANCY IMPLICATIONS — Animal reproduction studies have not been conducted with this combination; therefore, Bacitracin and Polymyxin B is considered pregnancy category C. See individual agents.
LACTATION — Excretion in breast milk unknown/use caution
BREAST-FEEDING CONSIDERATIONS — It is not known if bacitracin or polymyxin B is found in breast milk. The manufacturer recommends that caution be exercised when administering Bacitracin and Polymyxin B to nursing women. See individual agents.
PRICING — (data from drugstore.com)
Ointment (Bacitracin-Polymyxin B)
500-10000 units/g (3.5): $17.99
CANADIAN BRAND NAMES — LID-Pack®; Optimyxin®
INTERNATIONAL BRAND NAMES — Glubacida (MX); Miratracina (CO); Nebacetina (MX); Neobacitracine (BE); Neospor & iacute;n Dermico (MX); Polisulfade (PT); Polixin Ungena (MX); Polyfax (MY); Polysporin Ophthalmic (ZA); Tribiot (MX)
MECHANISM OF ACTION — See individual agents.
PHARMACODYNAMICS / KINETICS — See individual agents.
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